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Answer: Any grip combination that's comfortable can work well for a two-hander, but the most versatile grip combination is to have the left hand (of a right-hander) in an Eastern or Semi-Western forehand position and the right hand in a Continental backhand position. Having the right hand in a Continental or Eastern backhand position avoids the need to switch grips when you have to use that hand alone to stretch for a low or wide ball. If you're not getting enough topspin, you might try moving both hands slightly more counterclockwise (clockwise for a lefty).